Research Associate I, Analytical Development, Genomic Medicines Job at Alexion Pharmaceuticals,Inc.

Alexion Pharmaceuticals,Inc. Lexington, MA

Some opportunities happen only once in a lifetime - like a job where you have the chance to change lives. At Alexion, people living with rare and devastating diseases are our Guiding Star. We are driven to continuously innovate and create meaningful value in all we do to help patients and families fully live their best lives. We value the uniqueness and diversity of our employees and recognize that nurturing the diverse perspectives and strengths of our people translates into innovative breakthroughs for patients.


This is what you will do:

This position will play a key role in Alexion’s Genomics Medicine analytical development team interacting with external partners and other internal teams within the technology development group. The research associate will follow established standard operating procedures (SOPs) to perform molecular and biochemical based assays to characterize recombinant adeno-associated viral (rAAV) vectors and other gene editing modalities to support process development and testing of pre-clinical grade research products. This is a unique opportunity to join an innovative company and apply cutting edge techniques to enable drug discovery and development. If you share our passion and sense of urgency for finding a lasting cure for patients, and are looking for a dynamic, collaborative and fulfilling work environment, we invite you to join our team.

Candidates should be self-starters, comfortable with autonomy, and embrace opportunities to develop new medicines as part of a dynamic team in a start-up-like environment within Alexion.


You will be responsible for:

  • Performing analysis of rAAV gene editing vectors (qPCR, ddPCR, ELISA, SDS-PAGE, agarose gel electrophoresis)
  • Independently conducting assays for in-process and final products to determine product quality
  • Analyzing data and recording results in electronic lab notebook in a timely manner
  • Further development of existing assays for improved performance
  • Writing technical reports summarizing data
  • Preparing and delivering scientific presentations for internal/external use

You will need to have:

  • BS in Cell Biology, Biochemistry, Molecular Biology or related scientific discipline
  • 0-2 years of relevant academic or industry experience
  • Excellent attention to detail and accuracy in following protocols is necessary
  • Must have strong organizational and communication skills
  • Strong desire to learn multiple techniques and willingness to provide support as required
  • Excellent interpersonal and collaborative skills, and the ability to work independently and effectively in a highly dynamic environment
  • The duties of this role are generally conducted in an lab environment. As is typical of a lab-based role, employees must be able, with or without an accommodation to: lift 15 pounds unassisted; work comfortably in a controlled environment with and around biological, infectious, and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.

We would prefer for you to have:

  • Experience testing AAV or other types of biologics
  • Experience with the performance of routine biological assays including qPCR, ddPCR, ELISA, SDS-PAGE, and agarose gel electrophoresis is desirable
  • The ability and desire to learn new techniques if needed

#LIDI-1

#LI-Hybrid


Alexion is a global biopharmaceutical company focused on serving patients and families affected by rare diseases and devastating conditions through the discovery, development and commercialization of life-changing medicines. Headquartered in Boston, Massachusetts, Alexion has offices around the globe and serves patients in more than 50 countries. Further information about Alexion can be found at: www.alexion.com.


Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion has taken critical steps to protect colleagues, loved ones, and patients from COVID-19 and its variants. All US-based employees must comply with Alexion's COVID-19 vaccination mandate. Alexion provides exceptions based on applicable state law as well as reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding a legally required exemption or accommodation, please contact accommodations@Alexion.com. Alexion participates in E-Verify.


As a leading employer in our industry, Alexion offers a highly competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, and much more.


AstraZeneca completed its acquisition of Alexion, marking the creation of Alexion, AstraZeneca Rare Disease. If you're interested in career opportunities with AstraZeneca, click here.




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