This position works on novel exosome and RNA nanotechnology platform-based therapeutics development. The successful candidate will be responsible for upstream cell culture, downstream exosome purification, and the therapeutics loading process.

Primary Responsibilities include:

• Independently design and execute cell culture experiments related to the development, scale-up, and characterization of the cell culture process
• Establish linkage between upstream bioreactor parameters or media conditions to exosome yield and quality attributes
• Purify exosomes from the cell culture medium using ultracentrifugation or related method, and related process development and optimization
• Independently design and carry out in vitro assays for drug candidates under development on cell level and physiochemical property studies
• Hands-on experimentation for mice models
• Communicate effectively through written and oral means. Manage and maintain process data in an organized manner, this includes writing/revising SOPs, authoring technical reports, and tech transfer documents, and preparing scientific presentations as needed
• Participate and drive decision-making within the project team by actively engaging in and leading scientific and technical discussions

Desired Education and Skills Requirements:

• Training in cell biology or pharmaceutical science or related field, especially miRNA discovery studies
• Can operate cell culture independently (mammalian cell lines)
• Understand and can operate in vitro assay at the cell level (ELISA, qPCR, Western Blot, MTT Assay)
• Has experience with ultracentrifuge or Extracellular Vesicles research
• Has hands-on experience with animals

Required Qualifications:

• MS or Ph.D. in Cell Biology, Pharmaceutical Science, or related experience is required
• Experience with exosome research is preferred
• Strong organizational skills and attention to detail
• Exceptional written and verbal communication
• Good laboratory skills relating to cell culture
• Good record-keeping skills and experience with SOP and GLP
• Flexibility in workload, hours, and job duties to achieve team objectives
• Positive attitude, great work ethic, and ambition be an active listener and open to constructive feedback and suggestions

Candidates must be authorized to work in the U.S.

ExonanoRNA offers a competitive compensation and benefits package.

ExonanoRNA is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.