Research Associate I/Research Associate II, Analytical Development, Cell Production Job at United Therapeutics

United Therapeutics Manchester, NH 03101

The job details are as follows:
What We Do
United Therapeutics Corporation focuses on the strength of a balanced, value-creating biotechnology model. We are confident in our future thanks to our fundamental attributes, namely our commitment to quality and innovation, the power of our brands, our entrepreneurial culture and our bioinformatics leadership. We also believe that our determination to be responsible citizens - having a positive impact on patients, the environment and society - will sustain our success in the long term.

We currently have five approved products on the market and a long-term mission of providing an unlimited supply of transplantable organs for those who need them.

Our company was founded by an entrepreneur whose daughter was diagnosed with a life-threatening condition. She sought to find treatment options and a cure for her daughter and patients like her. We are founder-led, and relentless in our pursuit of "medicines for life". We continue to research and develop treatments for cardiovascular and pulmonary diseases, pediatric cancers and other orphan diseases.

In 2021, we became the first publicly-traded biotech or pharmaceutical company to take the form of a public benefit corporation (PBC). Our public benefit purpose is to provide a brighter future for patients through (a) the development of novel pharmaceutical therapies; and (b) technologies that expand the availability of transplantable organs. At the same time, we seek to provide our shareholders with superior financial performance and our communities with earth-sensitive energy utilization.

How you’ll contribute
The Research Associate II – Analytical Development will develop and execute analytical methods to support the production of iPS-derived cells and cellularized 3D scaffolds for the development of autologous 3D printed tissue engineered organs.
  • Perform and optimize various assays to support the production of iPS-derived cells including flow cytometry, immunocytochemical assessment, proliferation assays and other cell-based assays as needed
  • Perform and optimize methods for immunohistochemical staining, imaging and analysis of cellularized 3D scaffolds
  • Write and update test methods for analytical assays
  • Write and update standard operating procedures for operation and maintenance of laboratory equipment
  • Assist in the technical transfer of assays into the production team or to internal/external manufacturing or testing laboratories
  • Assist in cell studies to address technical and scientific challenges to expansion and differentiation of iPSC-derived cells
  • Access and utilize primarily literature sources to support and develop experimental plans
  • Record and manage use of materials and reagents needed to carry out experiments
  • Report and present hypothesis driven experimental results, data, and plans to other team members individually and at group meetings
  • Meet 1:1 with managers to review results and progress
  • Help maintain smooth operations of the lab, including maintenance of lab supplies, monitoring of equipment, providing general lab support, and helping identify areas for improvement
  • Follow proper procedures regarding laboratory safety, use of personal protective equipment, and handling of biohazard materials, including human or animal cells and tissues
  • Record all laboratory data in the in-house data management system(s)
  • Perform other duties as assigned

For this role you will need
Minimum Requirements
  • Bachelor’s Degree in Arts/Sciences (BA/BS) in cellular biology, developmental biology, biomedical engineering or related field
  • Aseptic Technique and mammalian cell culture
  • Ability to initiate and manage day-to-day tasks effectively, including multi-tasking, flexibility and adaptability
  • Ability to independently follow experimental methods and protocols
  • Comfortable working in a hands-on laboratory environment and have good attention to detail and good lab practices
Research Associate II:
  • 3+ years of experience in a cell biology, developmental biology or biomedical engineering environment
  • Imaging and microscopy
  • Flow cytometry or immunohistochemistry
Research Associate I:
  • 1+ years of experience in a cell biology, developmental biology or biomedical engineering environment
  • Knowledge of cell biology
Preferred Qualifications
  • Master’s degree (MA/MS/MBA) in cellular biology, developmental biology, biomedical engineering or related field
Research Associate II:
  • 3+ years of experience in process development of cell based or immunohistochemical imaging
  • 1+ years of experience in analytical development
Research Associate I:
  • 1+ years of experience in process development of cell based or immunohistochemical imaging
  • 1+ years of experience in analytical development
  • Imaging and microscopy
  • Flow cytometry or immunohistochemistry
At United Therapeutics, you’ll realize quickly that it is not an ordinary place to work! When you join our company, you will learn, grow, contribute, have fun, and be challenged... all while making a difference in the lives of our patients.
While United Therapeutics does not require vaccination for Covid-19 at this time, we strongly encourage all employees and visitors to remain up to date on vaccinations and boosters to protect one another from illness. Employees working in customer-facing roles must adhere and comply with customers’ credentialing guidelines, which may require vaccination against Covid -19, the influenza virus, and other illnesses that could be harmful to healthcare staff and patients.
United Therapeutics Corporation is an Equal Opportunity/Affirmative Action Employer - EOE Minorities / Females / Protected Veterans / Individuals with Disabilities



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