Research Scientist- Metabolic Engineering Job at Mascoma LLC

Mascoma LLC Lebanon, NH 03766

Main functions

The Research Scientist will join a team engineering yeast and bacteria with novel capabilities for use across Lallemand’s business units. The Research Scientist will play a key role in developing and improving metabolic pathways for the production of “green” biochemicals. This position is based in Lebanon, NH and will report directly to the Project Manager. Responsibilities include:

· Use of state-of-the-art metabolic engineering approaches to design, build and test microbial strains to achieve project goals.

· Generation of new hypotheses and metabolic pathways by mining scientific literature and in-house data and models.

· Collaborating with researchers in strain engineering, analytical chemistry, bioinformatics, fermentation, and process development to achieve project milestones.

· Training, mentoring and supervising junior team members

· Authoring reports and presentations

Minimum Qualifications:

· PhD in metabolic engineering, synthetic biology, genetics, biochemistry, biochemical engineering, microbiology or related field.

· Strong core competency in metabolic engineering and small-scale fermentation processes.

· Ability to design and analyze experiments generating diverse data streams (transcriptomics, proteomics, metabolomics, genomics) to guide metabolic pathway development

· Working knowledge of genetics, gene regulation, synthetic biology, and biochemistry

· Good troubleshooting skills to deal with technical problems

· Demonstrated experience generating high quality data, and managing to a timeline

Preferred in an ideal candidate:

· Experience introducing and optimizing new metabolic pathways into a microbial host organism

· Hands-on experience in the area of bacteria or yeast research

· Familiarity with microbial physiology and protein engineering

· Familiarity with a range of synthetic biology techniques (e.g. Golden Gate / MoClo, Gibson Assembly)

· Familiarity with protein/enzyme engineering and expression in microbial hosts

· Excellent oral and written communication skills

· Varied educational and lab experiences enabling the development of new approaches

· Experience with Geneious, Benchling, and JMP platforms

Organization

Lallemand Inc. is a privately held Canadian company, founded at the end of the 19th century, specializing in the development, production and marketing of yeasts and bacteria. The company is comprised of 12 major business units, each focused on specific applications of yeast and bacteria, with operations and management throughout the world. Corporate offices for the parent company Lallemand Inc. are based in Montreal, Canada. Today, Lallemand employs more than 4000 people working across more than 45 countries, on 5 continents.

Lallemand conducts its R&D activities not only through internal projects, including at Mascoma LLC, but also in collaboration with many universities and other governmental and private research institutions around the world. Research and development is a major element in successfully identifying and satisfying the needs of the market segments in which Lallemand strives to play an active and leading role.

Mascoma LLC, part of the Corporate R&D business group, is a recognized leader in advanced bioconversion products for use in the production of fuels and chemicals from biomass sources. Mascoma also applies its cutting-edge synthetic biology, analytical chemistry, and fermentation technologies to develop and deliver innovative products across all markets served by Lallemand. Here a few examples of some of the commercial products that have come out of the Mascoma labs:

· Sourvisiae® a bioengineered ale yeast strain capable of producing lactic acid in sour-style beer production

· Transferm®_ Yield+ _a yeast strain engineered to express glucoamylase and reduce glycerol in corn ethanol production

· FiberFerma bioengineered yeast capable of fermenting sugars in cellulosic fuel production

· SucraMax® a bioengineered yeast built to increase yield for the Brazilian sugarcane ethanol recycle fermentation

Mascoma is an equal opportunity employer and offers competitive compensation in addition to a package of benefits including: medical, dental, and eye care insurance; a 401K program and matching contributions; paid vacation time, holidays, and floating holidays; tuition reimbursement for ongoing education; and schedule flexibility, among others. We continually aim to increase the diversity and inclusiveness of our workforce, recognizing that fresh perspectives and diverse life experiences bring about the new ideas and creativity that make our team succeed.

Job Type: Full-time

Pay: $90,000.00 - $110,000.00 per year

Benefits:

  • 401(k)
  • 401(k) matching
  • Dental insurance
  • Flexible schedule
  • Flexible spending account
  • Health insurance
  • Health savings account
  • Life insurance
  • Paid time off
  • Parental leave
  • Relocation assistance
  • Tuition reimbursement
  • Vision insurance

Schedule:

  • Monday to Friday

Supplemental pay types:

  • Bonus pay
  • Signing bonus

COVID-19 considerations:
Masks are worn at times of heightened COVID cases in the local area and when required by local ordinances. Remote work is also encouraged when possible.

Education:

  • Doctorate (Required)

Experience:

  • Metabolic Engineering: 1 year (Preferred)

Work Location: One location




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