Scientist, IPSC Culture, Moderna Genomics Job at Moderna Therapeutics
The Role:
As part of our vision, Moderna is committed to invest in R&D to further expand our impact on patients. We are building an independent research and business unit for genomic medicines, called Moderna Genomics (mGx) based in Technology Square, Cambridge, MA. mGx will be an innovation engine for the company focused on discovering and delivering the next generation of in vivo gene editing and nonviral gene therapies and our ultimate vision is to enable Personalized Gene Editing.
Moderna Genomics, Gene editing and DNA repair team in Technology Square, Cambridge, MA seeks an enthusiastic, experienced, and motivated scientist to contribute to portfolio expansion initiatives. The successful candidate will possess a curious scientific mind, flexible intellect, and the ability to effectively matrix with cross-functional teams. The candidate will leverage his/her/their deep scientific expertise in IPSC culture to help develop and characterize preclinical models of disease targets. This role will have the opportunity to make an impact through pioneering foundational protocols and experimental strategy leveraging a broad array of molecular and cellular biological approaches. He/she/they will be key contributors to building the culture for this new initiative.
Here’s What You’ll Do:
Apply deep expertise in IPSC culture, biology, and differentiation
Design, develop, and deploy a variety of assays spanning a range of approaches including qPCR, Westerns, capillary electrophoresis westerns (Protein Simple), MSD/ELISA, and other molecular and cellular biological techniques to characterize IPSC cels
Collaborate with core functional groups to execute specialized analyses (e.g. computational biology, in vivo pharmacology, protein engineering, disease experts)
Design and oversee the execution and propagation of cell lines and model systems
Serve a subject matter expert
Here’s What You’ll Bring to the Table:
PhD in Cell or Molecular Biology, Genetics or related field or BS/MS degree in a relevant scientific discipline with 2-5 years of laboratory experience in academia or industry
Hands-on experience with undifferentiated iPSC culture and maintenance
Experience with in vitro differentiation of iPSC, preferably into hepatocytes
Experience managing interactions with CROs
Molecular biology skills including mammalian cell DNA/RNA extraction, PCR/RT-PCR/qPCR
Experience with genomic editing using CRISPR a plus
Familiarity with cellular biology techniques including, immunocytochemistry, high-content imaging, image analysis, western blot, cell-based assays
Ability to execute, troubleshoot and analyze experiments and to interpret results
Precise documentation of procedures and results in compliance with Electronic Lab Notebook guidelines
Strong interpersonal and organizational skills
Good oral and written communication skills
Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:
Highly competitive and inclusive medical, dental and vision coverage options
Flexible Spending Accounts for medical expenses and dependent care expenses
Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
Family care benefits, including subsidized back-up care options and on-demand tutoring
Free premium access to fitness, nutrition, and mindfulness classes
Exclusive preferred pricing on Peloton fitness equipment
Adoption and family-planning benefits
Dedicated care coordination support for our LGBTQ+ community
Generous paid time off, including:
401k match and Financial Planning tools
Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
Complimentary concierge service including home services research, travel booking, and entertainment requests
Free parking or subsidized commuter passes
Location-specific perks and extras!
Candidates should be aware that Moderna currently maintains a policy requiring all US-based employees to be fully vaccinated against COVID-19 and receive a booster shot once eligible . Newly hired employees must be vaccinated and boosted prior to their employment start date. Moderna is an equal opportunity employer and will provide a reasonable accommodation to those unable to be vaccinated or receive a booster where it is not an undue hardship to the company to do so as provided under federal, state, and local law.
About Moderna
In over 10 years since its inception, Moderna has transformed from a research-stage company advancing programs in the field of messenger RNA (mRNA), to an enterprise with a diverse clinical portfolio of vaccines and therapeutics across seven modalities, a broad intellectual property portfolio in areas including mRNA and lipid nanoparticle formulation, and an integrated manufacturing plant that allows for rapid clinical and commercial production at scale. Moderna maintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science and rapid scaling of manufacturing. Most recently, Moderna's capabilities have come together to allow the authorized use and approval of one of the earliest and most effective vaccines against the COVID-19 pandemic.
Moderna's mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and autoimmune diseases. Moderna has been named a top biopharmaceutical employer by Science for the past seven years. To learn more, visit www.modernatx.com .
Moderna is a smoke-free, alcohol-free and drug-free work environment.
Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. #LI-JL2
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As part of our vision, Moderna is committed to invest in R&D to further expand our impact on patients. We are building an independent research and business unit for genomic medicines, called Moderna Genomics (mGx) based in Technology Square, Cambridge, MA. mGx will be an innovation engine for the company focused on discovering and delivering the next generation of in vivo gene editing and nonviral gene therapies and our ultimate vision is to enable Personalized Gene Editing.
Moderna Genomics, Gene editing and DNA repair team in Technology Square, Cambridge, MA seeks an enthusiastic, experienced, and motivated scientist to contribute to portfolio expansion initiatives. The successful candidate will possess a curious scientific mind, flexible intellect, and the ability to effectively matrix with cross-functional teams. The candidate will leverage his/her/their deep scientific expertise in IPSC culture to help develop and characterize preclinical models of disease targets. This role will have the opportunity to make an impact through pioneering foundational protocols and experimental strategy leveraging a broad array of molecular and cellular biological approaches. He/she/they will be key contributors to building the culture for this new initiative.
Here’s What You’ll Do:
Apply deep expertise in IPSC culture, biology, and differentiation
Design, develop, and deploy a variety of assays spanning a range of approaches including qPCR, Westerns, capillary electrophoresis westerns (Protein Simple), MSD/ELISA, and other molecular and cellular biological techniques to characterize IPSC cels
Collaborate with core functional groups to execute specialized analyses (e.g. computational biology, in vivo pharmacology, protein engineering, disease experts)
Design and oversee the execution and propagation of cell lines and model systems
Serve a subject matter expert
Here’s What You’ll Bring to the Table:
PhD in Cell or Molecular Biology, Genetics or related field or BS/MS degree in a relevant scientific discipline with 2-5 years of laboratory experience in academia or industry
Hands-on experience with undifferentiated iPSC culture and maintenance
Experience with in vitro differentiation of iPSC, preferably into hepatocytes
Experience managing interactions with CROs
Molecular biology skills including mammalian cell DNA/RNA extraction, PCR/RT-PCR/qPCR
Experience with genomic editing using CRISPR a plus
Familiarity with cellular biology techniques including, immunocytochemistry, high-content imaging, image analysis, western blot, cell-based assays
Ability to execute, troubleshoot and analyze experiments and to interpret results
Precise documentation of procedures and results in compliance with Electronic Lab Notebook guidelines
Strong interpersonal and organizational skills
Good oral and written communication skills
Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:
Highly competitive and inclusive medical, dental and vision coverage options
Flexible Spending Accounts for medical expenses and dependent care expenses
Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
Family care benefits, including subsidized back-up care options and on-demand tutoring
Free premium access to fitness, nutrition, and mindfulness classes
Exclusive preferred pricing on Peloton fitness equipment
Adoption and family-planning benefits
Dedicated care coordination support for our LGBTQ+ community
Generous paid time off, including:
- Vacation, sick time and holidays
- Volunteer time to participate within your community
- D iscretionary year-end shutdown
- Paid sabbatical after 5 years; every 3 years thereafter
401k match and Financial Planning tools
Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
Complimentary concierge service including home services research, travel booking, and entertainment requests
Free parking or subsidized commuter passes
Location-specific perks and extras!
Candidates should be aware that Moderna currently maintains a policy requiring all US-based employees to be fully vaccinated against COVID-19 and receive a booster shot once eligible . Newly hired employees must be vaccinated and boosted prior to their employment start date. Moderna is an equal opportunity employer and will provide a reasonable accommodation to those unable to be vaccinated or receive a booster where it is not an undue hardship to the company to do so as provided under federal, state, and local law.
About Moderna
In over 10 years since its inception, Moderna has transformed from a research-stage company advancing programs in the field of messenger RNA (mRNA), to an enterprise with a diverse clinical portfolio of vaccines and therapeutics across seven modalities, a broad intellectual property portfolio in areas including mRNA and lipid nanoparticle formulation, and an integrated manufacturing plant that allows for rapid clinical and commercial production at scale. Moderna maintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science and rapid scaling of manufacturing. Most recently, Moderna's capabilities have come together to allow the authorized use and approval of one of the earliest and most effective vaccines against the COVID-19 pandemic.
Moderna's mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and autoimmune diseases. Moderna has been named a top biopharmaceutical employer by Science for the past seven years. To learn more, visit www.modernatx.com .
Moderna is a smoke-free, alcohol-free and drug-free work environment.
Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. #LI-JL2
-
Please Note :
caminobluff.com is the go-to platform for job seekers looking for the best job postings from around the web. With a focus on quality, the platform guarantees that all job postings are from reliable sources and are up-to-date. It also offers a variety of tools to help users find the perfect job for them, such as searching by location and filtering by industry. Furthermore, caminobluff.com provides helpful resources like resume tips and career advice to give job seekers an edge in their search. With its commitment to quality and user-friendliness, Site.com is the ideal place to find your next job.